Poppers elicit their high by releasing nitric oxide (NO) when metabolised by the enzymes present in the plasma. NO is a free radical that stimulates vasodilation, increasing the oxygen supply to the brain. Oxygen is a source of free radicals & the unsaturated C=C double bonds are 1 of the their targets. Therefore, free radicals destroy the omega-3 essential fatty acids like DHA that you take to improve lipid profile & more importantly, retard neuron degeneration as 1/3 of the brain lipids is DHA. However, these free radicals can be quenced by antioxidants. Therefore, someone taking a lot of antioxidant supplements may not experience a high as great as someone who is taking little of such supplements & is on a poor diet with little fruits & vegetables. On the bright side, the antioxidants protect neurons from free radical attack & degeneration. Therefore, there is less brain damage for one whose diet is rich in antioxidants & is on antioxidant supplements. However, if you wish to retard aging & brain degeneration by supplementing with omega-3 & antioxidants, why use poppers?
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